Metabolic Biomarkers for ME/CFS: A New Test?

Robert Naviaux et al. have published new evidence of metabolite abnormalities somewhat specific to ME/CFS, indicating that we may soon have a - to date, lacking, and much needed - diagnostic biomarker for the disease vs. the laborious existing objective diagnostic: VO2 max repeat exercise tests

Consistent with my own integrative pathophysiological research/guidance, their data suggest that the condition centres on a common (maladaptive) systemic response to trauma (of varying kinds), rather than differential presentation of an illness stemming from a particular stressor

The aberration profile itself is said to resemble hibernation activity, arguably tantamount to organismic survival behaviour i.e. autonomic responses to systemic physiological threats such as malnutrition, dehydration, and hypoxia. Again, this conception is consistent with my review of the contemporary literature

Related article: The Economist