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PWME often carry above average levels of persistent organic and/or inorganic toxins (POPs/PIPs) which may complicate, or perhaps even underlie, their illness. Indeed, more broadly, there are now very few people on the planet who live free from exposure to harmful toxins/are immune to their effects. When approaching a personalised program of detoxification with one's GP/specialist, one may wish to cautiously consider the areas touched on below:


Testing for chemicals is rarely available, costly, imperfect and only half the story - the other half being a healthcare system (industry) disinterested in, and ill equipped to deal with, individuals with high toxic loads vs. more comfortable with the notion of (haphazardly) pumping us full of yet more chemicals!
• Fluids | Standard urine/blood tests only reveal circulating elements. ‘Provocation'/‘challenge' tests may be clearer but approach all chelation with caution
Hair | Exposures that have taken place within the last several months will show up but, as above, this may otherwise give a false-negative
• Biopsy | POPs are often fat soluble toxins that make their way to the fatty tissue where they are stored if not broken down. Further info

Synthetic Chelation

• DMSA | A chelator of heavy metals including mercury (Hg), lead (Pb), cadmium (Cd), that is NOT supposed to cross the blood-brain barrier (BBB)
EDTA | A chelator of heavy metals including Hg and Pb that is NOT supposed to cross the BBB
Dimercaprol | A chelator of heavy metals including Hg, Pb, and Cb that IS supposed to cross the BBB
• Resources | Detoxification Overview | Lets Talk Detox | Anecdotal review | Recovering Kids (Hg) | How To Detox Heavy Metals | Cadmium Toxicity

Organic Chelation

• Iodine | A chelator of heavy metals including mercury (Hg), lead (Pb), cadmium (Cd), that is NOT supposed to cross the blood-brain barrier (BBB)
• Cilantro | A chelator of Hg that IS supposed to cross the BBB. Cilantro is the leafy part of the herb coriander
• R-Lipoic Acid | A chelator of Hg that IS supposed to cross the BBB
• Vitamin C | A chelator of Cd and copper (Cu) that IS supposed to cross the BBB
• Melatonin | A chelator of Pb, Cd and Cu that IS supposed to cross the BBB

Organic Absorption

• Glutathione | The most potent natural antioxidant, often depleted in ME/CFS. Best delivered by IV as it is poorly metabolised, or else try NAC/whey form
• Chlorella | Binds toxins in the gut, aids intracellular detox, and supports glutathione. Chlorella + infrared sauna (below) may also ameliorate electro-sensitivity
• Activated Charcoal | Short-term use aids chemical toxin binding in the gut. Best to start only with a small amount and to be mindful of risks/side effects
• Resources | Food List | Cilantro & Chlorella | Copper Detox


• Lymphatic flow | Rebounding (e.g. using a trampoline), Chi machines, manual lymphatic drainage, and exercise all aid the transit of toxins out of the system
• Infrared | One of the most powerful ways to eliminate toxins is through sweat. Infrared therapy also reportedly improves joint/muscle pain/recovery. Deeper penetrating ‘Near Infrared' lamps are fast becoming the preferred variety - particularly among those, like myself, who are sensitive to EMFs and/or heat; Far Infrared Saunas (FIRS) warm the skin and surface tissues more effectively, however, and we can be more confident of their safe use at this stage. Further info
• Epsom salts | Epsom spa is a good way of detoxing e.g. supporting the above, and an effective treatment for joint pains/arthritis


• Detox | Some physicians associate certain physiological responses to grounding to detoxification responses, perhaps implying a role in detoxification
• Bone/joint health | Grounding reportedly has the capacity to improve a host of health indicators and even halt the progression of osteoporosis
Note | As grounding is associated with increased blood viscosity it may exacerbate supine hypertension so be careful attempting to ground whilst lying down


• Toxins | Pesticides, food additives, and contaminated water ought to be avoided
• Paleo | Aim for high protein, fat/lipids and fibre (raw foods, ideally - taking care over food safety) vs. low carbohydrate (particularly high GI/refined)
• Vitamins & Minerals | Aim for a diet rich in vitamins and minerals (esp zinc & selenium), particularly when chelating as this tends to deplete essential minerals


Adherence to a suitable detoxification program - in the context of effective mitigation of location effects - should bring about an improvement in inflammatory responsiveness; however, desensitisation therapies may still be worth pursuing in some cases e.g. where chemical/fungal/pollen/food sensitivities persist

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